The single-use bioreactor, derived from stainless steel bioreactor technology, simplifies operations and reduces the risk of cross-contamination in the cultivation of various cell lines.
The SUB500 is a stired-tank, disposable bioreactor for cultivating human, mammalian, and animal cells. lt combines the efficiency of single-use systems with the high performance of conventional stainless steel bioreactors. The single-use design eliminates tedious cleaning, sterilization, and reducing setup times. The unique stiring system brings better gas transfer and liquid mixing, thus achieving faster production speed and a higher yield. With a wide volume range from 50L to 2000L, the SUB500 is a perfect choice for lab, pilot-scale oiindustrial scale applications.

Features:

• Hardware, software and consumables form an efficient, easy-to-use and powerful cell culture platform that supports cell growth, cell viability and metabolic process
• Axial flow mixing and excellent material transfer effect
• Top quality accessories, stable run of system
• Modular design, supporting customization
• Three-level authority, audit trail, complete electronic data reporting, easy transfer and storage
• The touch screen software control function is rich, simple and intuitive, and the feedback system logic is clear
• Coarse bubble and micro bubble combining top overlay aeration and disposable reaction bag bottom sparging aeration design
• Complete FAT, SAT, 1Q/OQ files and services

Bioreactor Tank Design

• Stir

  • Using a low shear force downward pressure stirring paddle to form an axial flow
  • Fully mixing the materials in the tank and keeping the cells in the culture system under the suspension status to enable the sufficient contact of cells and nutrient substances
  • The low shear force stiring paddle disperses the bottom bubbles and evenly distributes them into the culture medium
  • lmproving the mass transfer efficiency between gas and liquid to meet the needs of cell culture
    

• Heating and cooling

  • Connect the PT1000 sensor with a doublelaver wall jacket and associate it with a TCU temperature control unit to ensure efficient heating, cooling, and uniformity of solution temperature. Provide temperature protection, over temperature alarm, and automatic stop of heating due to overheating
  • The software system complies with the standards for computer system from development to GMP production phase and relevantrequirements of GAMP5 and 21 CFR Part 11

• Control Cabinet Design

  • Control system adopts Siemens PLC, which works with sensor and hardware meeting cell culture requirements to form PlD closed loop control
  • 15" colour touch screen is used for local operation, fow and data display, dual data backup and has power-of protection function

SUB Stirred Bioreactor Bag

• Designed for SUB straight axis stirrered bioreactor
• Electrode interfaces are reserved for the reactor flexibly, including replenishing, PH, DO and temperature electrode interfaces
• Optional bubbling mode
• Culture bag uses 9101 film, double-layer package and after gamma irradiation sterilization
• Volume: 50L to 2000L

Specifications:

More information, pls click here to download the brochure.

We also provide customized services, please feel free to contact us (eshop@lab1st.com) if you need.

Product Brochure / Data Sheet

All the Standard Shipping package will be delivery by standard logistics, such as DHL, FedEX, UPS, etc (shipping terms: DAP). We also provide Sea Shipping, please contact us (eshop@lab1st.com) or chat with us online for real-time shipping cost. Please note that we are day off on the weekends and holidays.

If the merchandise is in stock, we will ship it within 3 to 7 business days for Standard Shipping and about 20 to 30 business days for Sea Shipping. If it is out of stock, we will inform you the estimated delivery time according to different products. All orders will be processed within 2 days (handing time).